產品詳情
Cat#：179P26
序列（三字母）：H-Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH? trifluoroacetate salt
序列（單字母）：FRVDEEFQSPFASQSRGYFLFRPRN-NH?
類似名：NMU-25 (human)
分子式：C???H???N??O??
分子量：3080.42
CAS#：312306-89-1
合成方法：Synthetic
存儲條件：-20 ± 5 °C
應用：Obesity Research
描述：Neuromedin U is a neuropeptide which is widely distributed in the gut and central nervous system. Initially isolated from porcine spinal cord it was named for its uterine contractile activity. In fasted rats neuromedin U expression in certain brain areas is lower than in fed rats. In animal studies with neuromedin-23 (rat) overnight food intake is significantly reduced indicating that neuromedin U may be a physiological regulator of food intake. IC?? values for the binding of neuromedin U-25 (human) to the human neuromedin U receptors NMU1R and NMU2R are 2.7 nM and 1.8 nM, respectively.
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