產品詳情
Cat#：163P02
序列（三字母）：H-Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH trifluoroacetate salt
序列（單字母）：MAPRGFSCLLLLTSEIDLPVKRRA
分子式：C???H???N??O??S?
分子量：2687.27
CAS#：330936-69-1
合成方法：Synthetic
存儲條件：-20 ± 5 °C
應用：Alzheimer′s Disease
描述：Humanin (HN) is a polypeptide suppressing neuronal cell death induced by several familial Alzheimer′s disease genes and by amyloid β-protein (1-43) (human). It has been shown that amyloid β-protein (1-40) and amyloid β-protein (1-42) secretion is not affected by humanin in F11 cells expressing the familial Alzheimer′s disease gene K595N/M596L-APP. Inhibitory actions on neuronal cell death triggered by K595N/M596L-APP directly and caused by amyloid β-protein have been suggested.
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